Biochemistry/Biochemistry MCQ Set 2 Sample Test,Sample questions

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Question: 
 How many mitochondrial proteins are encoded in nuclear genes and imported into mitochondria after their synthesis?

1. 300

2.500

3.700

4.900

Question: 
 Recombinant DNA construction involves ____________

1.Cleaving DNA with a restriction endonuclease and joining with polymerase

2.Cleaving and joining DNA with restriction endonuclease

3.Cleaving DNA with a restriction endonuclease and joining with ligase

4.Cleaving DNA with ligase and joining with endonuclease

Question: 
 Which effects the increased levels of hydrogen ions in the inter-membrane space of the mitochondria?

1.Decreased levels of chemiosmosis

2.Increased levels of water in inter-membrane space

3.Increase ATP production

4.Decreased levels of oxidative phosphorylation

Question: 
 Which of the following enzymes acts in the pentose phosphate pathway?

1.6-phosphogluconate dehydrogenase

2.Pyruvate kinase

3.Glycogen phosphorylase

4.Aldolase

Question: 
 Which of the following has beads on a string structure?

1.Nucleosomes

2.Chromosomes

3.Heterochromatin

4.Chromatin

Question: 
 Which of the following is a measure of the effect of an enzyme’s concentration on flux through a multi-enzyme pathway?

1.Metabolic control

2.Response coefficient

3.Elasticity coefficient

4.Flux control coefficient

Question: 
 Which of the following is the correct sequence for the movement of electrons during the light-dependent reactions of plants?

1. P680, water, P700, NADP+

2. Water, P680, P700, NADP+

3.P700, P680, NADP+, water

4.Water, P700, NADP+, P680

Question: 
 Which of the following temperature best suits the growth and multiplication of transformed cells?

1. 25°C

2.26°C

3. 37°C

4.30°C

Question: 
 Which one of the following is the source of electrons in photosynthesis?
a) NADH
b) Water
c) Carbohydrates
d)  Which one of the following is the source of electrons in photosynthesis?

1.NADH

2.Water

3.Carbohydrates

4.CO2

Question: 
Anabolism and catabolism are chemically linked in the form of __________

1.ASP

2.ADP

3.ATP

4.Phosphodiester linkage

Question: 
Arrangement of nucleotides in DNA can be seen using which of the following instruments?

1.Electron microscope

2. Light microscope

3.X-Ray crystallography

4.Ultracentrifuge

Question: 
Biochemistry MCQ on Lipids, Biological Membranes and Transport
1. The number of milligrams of KOH required to neutralize the free and combined fatty acid in one gram of a given fat is called __________

1.Polenske number

2.Acid number

3.Saponification number

4.Iodine number

Question: 
Complex 4 is also known as _________

1.Cytochrome oxidase

2.NADH dehydrogenase

3.Succinate dehydrogenase

4.Cytochrome bc1 complex

Question: 
How many carbons are present in HMG co-A?

1.12

2.8

3.6

4.4

Question: 
How many steps are catalyzed by different enzymes in glycolysis and gluconeogenesis?

1.3

2.4

3.1

4.2

Question: 
How many types of signal transducers are there?

1.6

2.7

3.8

4.4

Question: 
Long-chain fatty acids are oxidized step-wise in one-carbon unit starting from ____________

1.Aliphatic end

2.Carboxyl end

3. a and b

4.None of the mentioned

Question: 
Meristem culture helps in developing which of the following?

1.Hybrid plants

2.Virus free plants

3.Tall plants

4.Disease resistant plants

Question: 
Migration of cancerous cells from the site of origin to other part of the body forming secondary tumors is called ___________

1.Proliferation

2.Diapedesis

3.Apoptosis

4.Metastasis

Question: 
What is the effect of the excessive rate of apoptosis?

1.AIDS

2.Fever

3.Atrophy

4.Sneezing

Question: 
When visual stimulus reaches receptors in retina of eye, first process involving absorption of physical energy by receptors is?

1.Coding

2.Adaptation

3.Transduction

4.Reception

Question: 
Whenever the cell’s ATP supply is depleted, which of the following enzyme’s activity is increased?

1.Pyruvate kinase

2.Phosphofructokinase-1

3.Hexokinase

4.Glucokinase

Question: 
Whenever the cell’s ATP supply is depleted, which of the following enzyme’s activity is increased?

1.Pyruvate kinase

2.Phosphofructokinase-1

3.Hexokinase

4.Glucokinase

Question: 
Which compounds are responsible for the coordinated regulation of glucose and glycogen metabolism?

1.Fructose 2, 6-bisphosphate

2.Acetyl co-A

3.NADH

4.NAD+

Question: 
Which is the first step in the catabolism of most L-amino acids once they have reached the liver is promoted?

1.Glutamine synthase

2.Glutamate dehydrogenase

3.Glutaminase

4.Amino transferases

Question: 
Which is the major factor(s) determining whether glucose is oxidized by aerobic or anaerobic glycolysis?

1.Presence of high AMP

2. NADH and the ATP/ADP ratio

3.Ca+2

4.FADH2

Question: 
Which of the following are exclusively glucogenic?

1.Lysine

2.Leucine

3.Threonine

4.Arginine

Question: 
Which of the following catalyzes reactions that incorporate nitrogen derived from glutamine?

1.Glutamine synthase

2.Glutamine amidotransferase

3.Adenylyltransferase

4.Glutamate synthase

Question: 
Which of the following catalyzes the cutting of PIP2 into 2 moles of IP3 and diacylglycerol in cell signaling?

1.Phosphodiesterase

2.Phosphokinase C

3.Phospholipase C

4.Lipokinase

Question: 
Which of the following class of drugs reduce the levels of fatty acids circulating in the blood?

1.Amphetamines

2.Thiazolidinediones

3.Synthetic cannabinoids

4.Cathinones

Question: 
Which of the following condenses acyl and malonyl groups?

1.Acetyl co-A ACP transacetylase

2.Malonyl co-A ACP transferase

3.β-ketoacyl ACP synthase

4.Acyl carrier protein

Question: 
Which of the following directly phosphorylate tyrosines to start a kinase protein enzymatic cascade?

1.Receptor threonine kinase

2.Receptor serine kinase

3.Receptor tyrosine kinase

4.Receptor guanylyl cyclases

Question: 
Which of the following drug is used to terminate early pregnancies?

1.Victoza

2.Glucophage

3.RU486

4.Metformin

Question: 
Which of the following enzyme is responsible for the conversion of glucose 1-phosphate to glucose 6-phosphate?

1.Epimerase

2.Phosphoglucomutase

3.Glycogen phosphorylase

4.Isomerase

Question: 
Which of the following enzyme is used in PCR?

1.EcoRII

2.EcoRI

3.Taq DNA polymerase

4.HRP

Question: 
Which of the following enzyme is used in PCR?

1.EcoRII

2.EcoRI

3.Taq DNA polymerase

4.HRP

Question: 
Which of the following enzymes remove supercoiling in replicating DNA ahead of the replication fork?

1.Topoisomerases

2.Primases

3.Helicases

4.DNA polymerases

Question: 
Which of the following gives rise to γ-amino butyrate?

1.Pyruvate decarboxylation

2.Glutamine synthase

3.Glutamate synthase

4.Glutamate decarboxylation

Question: 
Which of the following gives rise to methionine, threonine, and lysine?

1.Glutamate

2.Serine

3.Pyruvate

4.Aspartate

Question: 
Which of the following has the lowest level of chromosome organization?

1.30nm fiber

2.Nucleosome

3.Solenoid

4.None of these

Question: 
Which of the following histones shows more sequence similarity among eukaryotic species?

1.H2A

2.H3

3.H1

4.H2B

Question: 
Which of the following hormone is responsible for the activation of phospholipase C?

1.Adrenaline

2.Serotonin

3.Cortisol

4.Vasopressin

Question: 
Which of the following inactivates the 60S subunit of eukaryotic ribosomes?

1.Ricin

2.Chloramphenicol

3.Cycloheximide

4.Diphtheria toxin

Question: 
Which of the following involves carrying genetic information from DNA for protein synthesis?

1.sn-RNA

2.r-RNA

3.m-RNA

4.t-RNA

Question: 
Which of the following is a choline-containing lipid?

1.Phosphatidylethanolamine

2.Phosphatidylserine

3.Sphingomyelin

4.Phosphatidylglycerol

Question: 
Which of the following is a intracellular second messengers?

1.Glycine

2.Glutamate

3.Acetylcholine

4.IP3

Question: 
Which of the following is a measure of how responsive the enzyme is to changes in the concentration of a metabolite?

1.Metabolic control

2.Response coefficient

3.Flux control coefficient

4.Elasticity coefficient

Question: 
Which of the following is a measure of how responsive the enzyme is to changes in the concentration of a metabolite?

1.Metabolic control

2.Response coefficient

3. Flux control coefficient

4.Elasticity coefficient

Question: 
Which of the following is an example of RNA-dependent DNA polymerase?

1. RNA polymerase II

2. DNA ligase

3.Reverse transcriptase

4.RNA polymerase I

Question: 
Which of the following is degraded to methylmalonyl semialdehyde?

1.Leucine

2.Thymine

3.Glutamine

4.Tyrosine

Question: 
Which of the following is involved in the bio-signaling pathway that includes membrane turnover and exocytosis?

1. Phosphatidyl glycerol

2.Phosphatidylinositol

3.Phosphatidyl glycerol and myoinositol

4.Myoinositol

Question: 
Which of the following is not a factor determining the activity of an enzyme?

1.Nucleotides

2.Association with regulatory protein

3.Sequestration

4.Allosteric regulation

Question: 
Which of the following is not a flavoprotein?

1.NADH dehydrogenase-Qreductase

2.Succinate dehydrogenase

3.Xanthine oxidase

4.Cytochrome c

Question: 
Which of the following is not an important precursor of glucose in animals?

1.Pyruvate

2.Glucose 6-phosphate

3.Lactate

4.Glycerol

Question: 
Which of the following is not an important precursor of glucose in animals?

1.Pyruvate

2.Glucose 6-phosphate

3.Lactate

4.Glycerol

Question: 
Which of the following is not correct about phosphorylation by IRS on serine residue?

1.Target tissues fail to respond to circulating insulin

2.It increases insulin levels

3.It is an inhibitory phosphorylation

4.It is molecular mechanism for insulin resistance

Question: 
Which of the following is not involved in the post-transcriptional processing of t-RNA?

1.Attachment of poly-A tail

2.Base modulation

3.Attachment of CCA arm

4.Splicing

Question: 
Which of the following is termed as conserved gene order?

1.Microarray

2. Ortholog

3.Synteny

4.Paralog

Question: 
Which of the following is the first amino group entering into urea cycle?

1.Argininosuccinate

2.Cituilline

3.Carbamoyl phosphate

4.Ornithine

Question: 
Which of the following is the prosthetic group of NADH dehydrogenase?

1.FAD

2. FMN

3.NADH

4.NADPH

Question: 
Which of the following is the study of energy relationships and conversions in biological systems?

1.Biochemistry

2.Biotechnology

3.Biotechnology

4.Bioenergetics

Question: 
Which of the following is true about the Z-DNA helix?

1.It has fewer base pairs per turn than B-DNA

2.It tends to be found at the 3’ end of the genes

3.It has alternating GC sequences

4.It is a permanent conformation of DNA

Question: 
Which of the following is true about tm?

1.The higher the content of G ≡ C base pairs, the lower the tm

2.The higher the content of A = T base pairs, the higher the tm

3.It can be termed as renaturation temperature

4.The higher the content of G ≡ C base pairs, the higher the tm

Question: 
Which of the following mechanisms will remove uracil and incorporate the correct base?

1.Nucleotide excision repair

2. Direct repair

3.Base excision repair

4.Mismatch repair

Question: 
Which of the following membrane lipids have a direct glycosidic linkage between the head-group sugar and the backbone glycerol?

1.Ether lipids

2.Sphingolipids

3.Glycolipids

4.Phospholipids

Question: 
Which of the following membranes contain low cholesterol and high cardiolipin?

1.Cell wall

2.Inner mitochondrial membrane of the hepatocyte

3.Myelin sheath

4.Plasma membrane

Question: 
Which of the following occurs in meiosis but not in mitosis?

1.Pairing of homologous chromosomes at metaphase plate

2.Separation of sister chromatids at anaphase

3.Attachment of spindle fibers to kinetochore

4. Replication of DNA prior to start of cell division

Question: 
Which of the following operates at an important intersection of carbon and nitrogen metabolism?

1.lutamine synthase

2.Glutaminase

3.Glutaminase

4.Amino transferases

Question: 
Which of the following plays a substantial role in linking together sister chromatids immediately after replication?

1.Topoisomerases

2.Histones

3.Condensins

4.Cohesins

Question: 
Which of the following process occurs in regions where no large–scale sequence similarity is apparent?

1. Site specific recombination

2.Replicative recombination

3.Homologous genetic recombination

4.Non-homologous recombination

Question: 
Which of the following produces pyruvate?

1.Alanine

2.Leucine

3. Isoleucine

4.Lysine

Question: 
Which of the following proteins does not function in cell-cell interaction?

1.Cadherin

2.Cytochrome c

3.Integrin

4.N-CAM

Question: 
Which of the following temperature best suits the growth and multiplication of transformed cells?

1.25°C

2.26°C

3.37°C

4.30°C

Question: 
Which of the following temperature best suits the growth and multiplication of transformed cells?

1.25°C

2.26°C

3.37°C

4.30°C

Question: 
Which position of a codon is said to wobble?

1.Fourth

2.First

3.Second

4.Third

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