All engineering students should learn mechanics, mathematics and how to do computation.
I II III IV
Which of the above underlined parts of the sentence is not appropriate?1.I
2.II
3.III
4.IV
An automobile plant contracted to buy shock absorbers from two suppliers X and Y. X supplies 60% and Y supplies 40% of the shock absorbers. All shock absorbers are subjected to a quality test. The ones that pass the quality test are considered reliable. Of X's shock absorbers, 96% are reliable. Of Y's shock absorbers, 72% are reliable. The probability that a randomly chosen shock absorber, which is found to be reliable, is made by Y is
1.0.288.
2. 0.334
3.0.667
4.0.720
Consider the data set 14, 18, 14, 14, 10, 29, 33, 31, 25. If you add 20 to each of the values, then
1.both mean and variance change
2. both mean and variance are unchanged
3.the mean is unchanged, variance changes
4.the mean changes, the variance is unchanged
Determine the correctness or otherwise of the following Assertion (a) and Reason (r). Assertion: Immobilization of plant cells can enhance secondary metabolite production during bioreactor cultivation. Reason: Immobilization protects the plant cells from shear forces in the bioreactor.
1.Both (a) and (r) are true and (r) is the correct reason for (a).
2. Both (a) and (r) are true but (r) is not the correct reason for (a).
3.(a) is true but (r) is false.
4. (a) is false but (r) is true.
Given the sequence of terms, AD CG FK JP, the next term is
1.OV
2.OW
3.PV
4.PW
In a factory, two machines M1 and M2 manufacture 60% and 40% of the autocomponents respectively. Out of the total production, 2% of M1 and 3% of M2 are found to be defective. If a randomly drawn autocomponent from the combined lot is found defective, what is the probability that it was manufactured by M2?
1.0.35
2.0.45
3.0.5
4. 0.4
In a genetic study, 80 people were found to have alleles for polydactyly. Only 36 of them were polydactylous. What is the extent of penetrance percentage? ________
1. 40
2.45
3.50
4.60
In a muscle, the extracellular and intracellular concentrations of Na+ are 150 mM and 12 mM, and those of K+ are 2.7 mM and 140 mM, respectively. Assume that the temperature is 25oC and that the membrane potential is -60 mV, with the interior more negatively charged than the exterior. (R = 8.314 J mol-1 K-1; F = 96.45 kJ mol-1 V-1) The free energy change for the transport of two K+ into the cell is
1.+8.0 kJ/molB.
2. +11.6 kJ/mol
3.+19.6 kJ/mol
4.+31.2 kJ/mol
In nature, the horizontal gene transfer across bacteria is mediated by
1.gene cloning followed by transformation
2. conjugation and transformation
3.conjugation only
4.transformation only
Match the entries in Group I with the methods of sterilization in Group II.
Group I Group II
P. Serum 1. Autoclave
Q. Luria broth 2. Membrane filtration
R. Polypropylene tubes 3. UV irradiation
S. Biological safety cabinets 4. Gamma irradiation
5. Dry heat1. P-5, Q-3, R-1, S-4
2.P-1, Q-4, R-5, S-3
3.P-2, Q-1, R-4, S-3
4.P-4, Q-1, R-3, S-5
Match the high energy compounds in Group I with the biosynthetic pathways for the molecules in Group II. Group I Group II P. GTP 1. Fatty acid Q. UTP 2. Phospholipid R. CTP 3. Protein S. Acyl coenzyme A 4. Peptidoglycan
1.P-3, Q-2, R-4, S-1
2.P-2, Q-4, R-3, S-1
3.P-4, Q-3, R-1, S-2
4.P-3, Q-4, R-2, S-1
Select the pair that best expresses a relationship similar to that expressed in the pair: water: pipe::
1.cart: road
2.electricity: wire
3.sea: beach
4. music: instrument
The RNA primer synthesized during the replication process in bacteria is removed by
1.DNA gyrase
2.primase
3.DNA polymeraseI
4.DNA polymerase II
The suitable substitution matrix to align closely related sequences is
1.PAM 250 or BLOSSUM 80
2.PAM 40 or BLOSSUM 80
3.PAM 120 or BLOSSUM 40
4.PAM 250 or BLOSSUM 40
Which one of the following options is the closest in meaning to the word given below? Mitigate Diminish
1.They gave us the money back less the service charges of Three Hundred rupees.
2.Divulge
3.Dedicate
4.Denote
. Determine the correctness or otherwise of the following Assertion (a) and Reason (r). Assertion: In direct somatic embryogenesis, embryos are developed without going through callus formation. Reason: This is possible due to the presence of pre-embryonically determined cells.
1.Both (a) and (r) are true but (r) is not the correct reason for (a)
2.(a) is false but (r) is true
3. (a) is true but (r) is false
4.Both (a) and (r) are true and (r) is the correct reason for (a)
. The Laplace transform of f(t) = 2t + 6 is
1.1/s + 2/s2
2.3/s - 6/s2
3.6/s + 2/s2
4.-6/s + 2/s2
36. Determine the correctness or otherwise of the following Assertion (a) and Reason (r). Assertion: UPGMA method produces ultrametric tree. Reason:Sequence alignment is converted into evolutionary distances in UPGMA method.
1.Both (a) and (r) are true and (r) is the correct reason for (a)
2.Both (a) and (r) are true and (r) is not the correct reason for (a)
3.(a) is true but (r) is false
4.(a) is false but (r) is true
A bacterial culture (200 ïÂÂl containing 1.8 * 109 cells) was treated with an antibiotic Z (50 μg per ml) for 4 h at 37ËšC. After this treatment, the culture was divided into two equal aliquots. Set A: 100 μl was plated on Luria agar. Set B: 100 μl was centrifuged, the cell pellet washed and plated on Luria agar. After incubating these two plates for 24 h at 37ËšC, Set A plate showed no colonies, whereas the Set B plate showed 0.9 * 109 cells. This experiment showed that the antibiotic Z is
1.bacteriostatic
2.bacteriocidal
3.bacteriolytic
4.apoptotic
A batch bioreactor is to be scaled up from 10 to 10,000 liters. The diameter of the large bioreactor is 10 times that of the small bioreactor. The agitator speed in the small bioreactor is 450 rpm. Determine the agitator speed (rpm) of the large bioreactor with same impeller tip speed as that of the small bioreactor. _________
1.45
2.40
3.50
4.55
A callus of 5 g dry weight was inoculated on semi-solid medium for growth. The dry weight of the callus was found to increase by 1.5 fold after 10 days of inoculation. The growth index of the culture is _________
1. 0.3
2.0.5
3.0.7
4.0.9
A chemostat is operated at a dilution rate of 0.6 h-1. At steady state, the biomass concentration in the exit stream was found to be 30 g l-1. The biomass productivity (g l-1h-1) after 3h of steady state operation will be ___________
1.3
2.9
3.18
4.27
A complete restriction digestion of a circular plasmid (5000bp) was carried out with HindIII,BamHIandEcoRI individually. Restriction digestion yielded following fragments. Plasmid + HindIII→ 1200bp and3800bp Plasmid + BamHI→5000bp Plasmid + EcoRI→ 2500bp The number of sites for EcoRI,BamHIandHindIIIpresent on this plasmid are
1.EcoRI-2, BamHI-1, HindIII-2
2.EcoRI-1, BamHI-1, HindIII-
3. EcoRI-3, BamHI-2, HindIII-1
4.EcoRI-2, BamHI-2, HindIII-1
A DNA fragment of 5000bp needs to be isolated from E.coli (genome size 4*103kb) genomic library. The minimum number of independent recombinant clones required to represent this fragment in genomic library are
1.16*102
2.12*102
3.8*102
4.1.25*102
A fed batch culture was operated with intermittent addition of glucose solution at a flow rate of 200 ml h-1. The values of Ks, μm and D are 0.3 g l-1, 0.4 h-1 and 0.1 h-1, respectively. Determine the concentration of growth limiting substrate (gl-1) in the reactor at quasi-steady state. ____________
1.0.4
2.0.2
3.0.1
4.0.7
A solution was prepared by dissolving 100 mg of protein X in 100 ml of water. Molecular weight of protein X is 15,000 Da; Avogadro's number = 6.022 * 1023. Calculate the molarity(μM) of the resulting solution.
1.66.6
2.6.6
3.0.67
4.0.067
All professors are researchers Some scientists are professors Which of the given conclusions is logically valid and is inferred from the above arguments:
1.All scientists are researchers
2.All professors are scientists
3.Some researchers are scientists
4.No conclusion follows
An E. coli cell of volume 10-12 cm3 contains 60 molecules of lac-repressor. The repressor has a binding affinity (Kd) of 10-8 M and 10-9 M with and without lactose respectively, in the medium. The molar concentration of the repressor in the cell is
1. 0.1 nM
2.1 nM
3.10 nM
4.100 nM
An E. coli cell of volume 10-12 cm3 contains 60 molecules of lac-repressor. The repressor has a binding affinity (Kd) of 10-8 M and 10-9 M with and without lactose respectively, in the medium. Therefore the lac-operon is
1.repressed and can only be induced with lactose.
2.repressed and cannot be induced with lactose.
3.not repressed.
4.expressed only when glucose and lactose are present.
Calculate the percentage sequence identity for the pairwise alignment given below. _______ H E L L O “ Y E L L O W
1. 33.6 to 33.8
2. 25.9 to 26.1
3.54.7 to 54.9
4.66.5 to 66.7
Calculate the percentage sequence identity for the pairwise alignment given below. _______ H E L L O “ Y E L L O W
1. 33.6 to 33.8
2. 25.9 to 26.1
3.54.7 to 54.9
4.66.5 to 66.7
Determine the correctness or otherwise of the following Assertion (a) and Reason (r). Assertion: Cell mass yield of a methylotrophic yeast is more on methanol compared to glucose. Reason: Methanol has a greater degree of reductance compared to glucose.
1.Both (a) and (r) are correct and (r) is the correct reason for (a)
2.(a) is correct, (r) is false
3.(a) is false, (r) is correct
4. Both (a) and (r) are correct but (r) is not the correct reason for (a)
Determine the correctness or otherwise of the following Assertion (a) and Reason (r). Assertion: Plants convert fatty acids into glucose. Reason: Plants have peroxisomes.
1.Both (a) and (r) are true but (r) is not the correct reason for (a)
2.Both (a) and (r) are true but (r) is not the correct reason for (a)
3.(a) is true but (r) is false
4.(a) is false but (r) is true
Determine the correctness or otherwise of the following Assertion (a) and Reason (r). Assertion: The production of secondary metabolites in plant cell cultures is enhanced by the addition of elicitors. Reason: Elicitors induce the expression of enzymes responsible for the biosynthesis of secondary metabolites.
1. Both (a) and (r) are true but (r) is not the correct reason for (a)
2.Both (a) and (r) are true and (r) is the correct reason for (a)
3.(a) is true but (r) is false
4.(a) is false but (r) is true
Endogenous antigens are presented on to the cell surface along with
1. MHC-II
2.MHC-I
3.Fcγreceptor
4.complement receptor
Endogenous antigens are presented on to the cell surface along with
1. MHC-II
2.MHC-I
3.Fcγreceptor
4.complement receptor
Following table gives data on tourists from different countries visiting India in the year 2011. Which two countries contributed to the one third of the total number of tourists who visited India in 2011?
1.USA and Japan
2.USA and Australia
3.England and France
4.Japan and Australia
Human genome sequencing project involved the construction of genomic library in
1.bacterial artificial chromosome
2.pBR322
3.bacteriophage
4.pcDNA3.1
Human genome sequencing project involved the construction of genomic library in
1.bacterial artificial chromosome
2.pBR322C
3.bacteriophage
4.pcDNA3.1
Human genome sequencing project involved the construction of genomic library in
1.bacterial artificial chromosome
2.pBR322
3.bacteriophage
4.pcDNA3.1
Hypophosphatemia is manifested by an X-linked dominant allele.What proportion of the offsprings from a normal male and an affected heterozygous female will manifest the disease?
1.½ sons and ½ daughters
2.all daughters and no sons
3.all sons and no daughters
4.¼ daughters and ¼ sons
If |-2X + 9| = 3 then the possible value of |-X| - X2 would be:
1. 30
2.-30
3.-42
4.42
In a muscle, the extracellular and intracellular concentrations of Na+ are 150 mM and 12 mM, and those of K+ are 2.7 mM and 140 mM, respectively. Assume that the temperature is 25oC and that the membrane potential is -60 mV, with the interior more negatively charged than the exterior. (R = 8.314 J mol-1 K-1; F = 96.45 kJ mol-1 V-1) The free energy change for the transport of three Na+ out of the cell is
1.+1.5 kJ/mol
2.+17.4 kJ/mol
3.+18.9 kJ/mol
4.+36.3 kJ/mol
In nature, Agrobacterium tumefaciens mediated infection of plant cells leads to P. crown gall disease in plants Q. hairy root disease in plants R. transfer of T-DNA into the plant chromosome S. transfer of Ri-plasmid into the plant cell
1.S only
2.P and R only
3.Q and S only
4. Q only
Match the antibioticsin Group I with the targets in Group II. Group I Group II P. Sulfonamide 1. Peptidoglycan synthesis Q. Quinolones 2. Peptide chain elongation R. Erythromycin 3. Folic acid biosynthesis S. Cephalosporin 4. Topoisomerase
1.P-3, Q-4, R-1, S-2
2.P-2, Q-4, R-3, S-1
3. P-4, Q-1, R-2, S-3
4.3, Q-4, R-2, S-1
Match the commercial microbial sources in Group I with the products in Group II. Group I Group II P. Corynebacteriumlilium 1. 2,3-Butane di-ol Q. Klebsiellaoxytoca 2. Poly-β-hydroxybutyric acid R. Aspergillusniger 3. Glutamic acid S. Alcaligeneseutrophus 4. Citric acid
1.P-3,Q-1,R-2,S-4
2.P-3,Q-1,R-4,S-2
3.P-1,Q-3,R-2,S-4
4.P-1,Q-3,R-4,S-2
Match the downstream processes in Group I with the products in Group II. Group I Group II P. Solvent extraction 1. Lactic acid Q. Protein-A linked affinity chromatography 2. Penicillin R. Extractive distillation 3. Monoclonal antibody S. Salting out 4. Lipase
1.P-2, Q-3, R-1, S-4
2.P-4, Q-1, R-2, S-3
3. P-4, Q-1, R-3, S-2
4. P-2, Q-4, R-1, S-3
Match the entries in Group I with the entries in Group II. Group I Group II P. RNAse P 1. Polyadenylation Q. RNase H 2. Splicing R. snRNAs 3. Ribozymes S. CstF 4. DNA-RNAhybrids
1.P-3, Q-4, R-2, S-1
2.P-4, Q-3, R-2, S-1
3.P-3, Q-2, R-1, S-4
4.P-2, Q-4, R-1, S-3
Match the entries in Group I with the enzymes in Group II. Group I Group II P. NAD+ 1. Glutathione peroxidase Q. Selenium 2. Nitrogenase R. Pyridoxal phosphate 3. Lactate dehydrogenase S. Molybdenum 4. Glycogen phosphorylase
1.P-3, Q-2, R-4, S-1
2.P-4, Q-1, R-3, S-2
3.P-3, Q-1, R-4, S-2
4.P-3, Q-4, R-2, S-1
Match the entries in Group I with the process parameters in Group II. Group I Group II P. Clark electrode 1. Liquid level Q. Redox probe 2. Dissolved oxygen concentration R. Load cell 3. Vessel pressure S. Diaphragm gauge 4. pH (anaerobic process)
1.P-2, Q-1, R-3, S-4
2.P-4, Q-2, R-3, S-1
3.P-2, Q-4, R-1, S-3
4.P-2, Q-1, R-4, S-3
Match the entries in the Group I with the entries in Group II. Group I Group II P. Threading 1. Gene duplication Q. FASTA 2. Fold prediction R. Profile 3. HMM S. Paralogs 4. k-tuple
1.P-2, Q-1, R-3, S-4
2.P-2, Q-4, R-3, S-1
3.P-3, Q-4, R-2, S-1
4.P-1, Q-4, R-3, S-2
Match the herbicides in Group I with the target enzymes in Group II.
Group I Group II
P. Glyphosate 1. Nitrilase
Q. Bromoxynil 2. Acetolactatesynthetase
R. Sulphonylureas 3. Dehalogenase
S. Dalapon 4. 5-Enolpyruvyl shikimate3-phosphate
synthase
1.P-4, Q-1, R-2, S-3
2.P-2, Q-1, R-4, S-3
3.P-4, Q-3, R-2, S-1
4.P-3, Q-2, R-4, S-1
Match the organisms in Group I with the entries in Group II.
Group I Group II
P. Clostridium 1. Rods with teichoic acid in the cell wall
Q. Escherichia 2. Rods with endospores
R. Vibrio 3. Helical rods with flagella
S. Bacillus 4. Rods with LPS in the outer membrane
5. Curved rods with polar flagella1.P-2, Q-4, R-5, S-1
2.P-2, Q-1, R-5, S-4
3.P-5, Q-4, R-2, S-3
4. P-3, Q-2, R-1, S-4
Match the products in Group I with the applications in Group II. Group I Group II P. Digoxin 1. Muscle relaxant Q. Stevioside 2. Anti-cancer agent R. Atropine 3. Cardiovascular disorder S. Vinblastine 4. Sweetener
1. P-1, Q-4, R-3, S-2
2. P-3, Q-4, R-1, S-2
3. P-3, Q-4, R-1, S-2
4.P-2, Q-3, R-1, S-4
Match the terms in Group I with the ploidy in Group II. Group I Group II P. Disome 1. 2n + 1 Q. Monosome 2. 2n “ 1 R. Nullisome 3. n “ 1 S. Trisome 4. n + 1
1.P-4, Q-2, R-3, S-1
2.P-4, Q-3, R-1, S-2
3.P-2, Q-3, R-4, S-1
4.P-1, Q-4, R-3, S-2
Match the vitamins in Group I with the processes/reactions in Group II.
Group I Group II
P. Pantothenic acid 1 . Electron transport
Q. Vitamin B2 2. Transfer of 1-C units
R. Vitamin B6 3. Decarboxylation
S. Folic acid 4 . Fatty acid metabolism
5. Hydrolysis1.P-5, Q-2, R-4, S-1
2.P-4, Q-1, R-3, S-2
3.P-4, Q-2, R-1, S-3
4.P-2, Q-1, R-3, S-5
Of the two diploid species, species I has 36 chromosomes and species II has 28 chromosomes. How many chromosomes would be found in an allotriploid individual?
1.42 or 54
2.46 or 50
3.74 or 86
4.84 or 108
One percent of the cars manufactured by a company are defective. What is the probability (upto four decimals) that more than two cars are defective, if 100 cars are produced? __________
1.0.034 to 0.044
2.0.037 to 0.038
3.0.075 to 0.085
4. 0.048 to 0.058
Phylum proteobacteria is subdivided into α-, β-, Ã’-, δ- and õ-proteobacteria based on
1.G+C content
2.23S rRNA sequences
3. tRNA sequences
4. 16S rRNA sequences
The catalytic efficiency for an enzyme is definedas
1.kcat
2.vmax/kcat
3. kcat/km
4.kcat/vmax
The first humanized monoclonal antibody approved for the treatment of breast canceris A. RituximabB. CetuximabC. BevacizumabD. The first humanized monoclonal antibody approved for the treatment of breast canceris
1.Rituximab
2.Cetuximab
3.Bevacizumab
4. Herceptin
The Headmaster ___________ to speak to you. Which of the following options is incorrect to complete the above sentence?
1.is wanting
2.wants
3.want
4.was wanting
The Headmaster ___________ to speak to you. Which of the following options is incorrect to complete the above sentence?
1.is wanting
2.wants
3.want
4.was wanting
The maximum cell concentration (g l-1) expected in a bioreactor with initial cell concentration of 1.75 g l-1 and an initial glucose concentration of 125 g l-1 is (Yx/s = 0.6 g cell/g substrate) ________
1.67.4 to 67.
2. 43.4 to 43.6
3.87.4 to 87.6
4.76.7 to 76.9
The nucleotide analogue used in DNA sequencing by chain termination method is
1.1',3'-dideoxy nucleoside triphosphate
2.2',3'-dideoxy nucleoside triphosphate
3.',4'-dideoxy nucleoside triphosphate
4. 2',5'-dideoxy nucleoside triphosphate
The role of an adjuvant isto
1.prolong the persistence of antigen
2. cross link the antigen
3.increase the size of antigen
4.avoid inflammation
The solution of the following set of equations is x + 2y + 3z = 20 7x + 3y + z = 13 x + 6y + 2z = 0
1.x = -2, y = 2, z = 8
2. x = 2, y = -3, z = 8
3. x = 2, y = 3, z = -8
4.x = 8, y = 2, z = -3
The solution to dy/dx + y cot x = cosec x is
1.y = (c+x) cot x
2.y = (c+x) cosec x
3.y = (c + x) cosec x cot x
4.y = (c+x) cosec x/cot x
The total number of fragments generated by the complete and sequential cleavage of the polypeptide given below by Trypsin followed by CNBr is _________ Phe-Trp-Met-Gly-Ala-Lys-Leu-Pro-Met-Asp-Gly-Arg-Cys-Ala-Gln
1.5
2.10
3.15
4.25
Under alkaline conditions, DNA is more stable than RNA because
1.RNA forms secondary structures
2.RNA is a single stranded molecule
3.C. RNA has uracil in place of thymidine
4.RNA is susceptible to hydrolysis
Velocity of an object fired directly in upward direction is given by V = 80 - 32 t, where t (time) is in seconds. When will the velocity be between 32 m/sec and 64 m/sec?
1.(1, 3/2)
2. (1/2, 1)
3.(1/2, 3/2)
4. (1, 3)
Which of the following assertions are CORRECT? P: Adding 7 to each entry in a list adds 7 to the mean of the list Q: Adding 7 to each entry in a list adds 7 to the standard deviation of the list R: Doubling each entry in a list doubles the mean of the list S: Doubling each entry in a list leaves the standard deviation of the list unchanged
1.P, Q
2.Q, R
3.P, R
4. R,S
Which one of the following aminoacids in proteins does NOT undergo phosphorylation?
1.Ser
2.Thr
3.Pro
4.Tyr
Which one of the following is an ABC transporter?
1.multidrug resistance protein
2.acetylcholine receptorC.
3.bacteriorhodopsin
4.ATP synthase
Which one of the following modifications is common toboth protein and DNA?
1.SUMOylation
2.Nitrosylation
3.Methylation
4.Ubiquitination