Biochemistry-Biochemistry/Anti Bodies Sample Test,Sample questions

Monoclonal antibodies were first produced by

1.Georges Kohler and Cesar Milstein

2.Sarkar and Sommer

3.Selman Waksman

4. Edward Jenner and Louis Pasteur

The human IgG class of antibodies is divided into

1. five IgG classes

2. two IgG classes

3.three IgG classes

4.four IgG classes

The immunoglobulin fold is

1. found only in IgG molecules

2. a β-barrel composed of a three- and a four-stranded antiparallel β-sheet

3.both (a) and (b)

4.found six times in the IgG molecule

A polyclonal antibody response produced only in response to polymeric antigens

2. is produced by several B cells recognizing different pitopes on the same antigen

3.occurs during the lag phase of the immune response

4.violates clonal selection

A secondary antibody is an antibody that

1.has been used in prior experiments synthetically produced

3.binds to another antibody

4. is produced in boostered animals

Alum is an effective adjuvant because it

1.disaggregates the antigen. immunogenic for stem cells

3. is immunogenic for T cells

4. slows the release of antigen

Antibodies can be used

1.for the localization of proteins in the cell

2.for protein purification catalyze chemical reactions

4. all of the above

Antibodies in the human immune system can identify approximately 108 different molecules Which one of the following is correct?

1.This diversity is generated from 108 different immunoglobin genes

2.Many of these molecules are self-antigens

3.Most of these antibodies recognize proteins

4.Most of these antibodies recognize small organic molecules

Antibodies of the IgG class

1.consist of four subunits

2. are glycoproteins

3.are secreted into the bloodstream

4. all of the above

Antigenic determinants bind to which portions of an antibody?. 

1.Variable regions

2. Constant regions

3.Only light chains

4.Only heavy chains

Cleavage of an IgG molecule by a specific protease can produce antigen-binding site and two constant regions

2.two heavy chain-light chain dimers inactive mixture of oligopeptides

4.two Fab fragments and one Fc fragment

Each IgA antibody molecule consists of

1. four polypeptide chain and has two antigen binding site

2.two polypeptide chain and has one antigen binding site

3.three polypeptide chain and has two antigen binding site

4.two polypeptide chain and has two antigen binding site

Fab fragment has antigen binding site

2. two antigen binding site antibody binding site

4.two antibody binding site

he humoral immune response relies on the production of soluble proteins called

1. antibodies



4. none of these

he main function of antibodies is to

1.kill all the foreign bodies

2.generate antigens thus conferring immunization

3.protect the circulatory system

4.chemically combine with the antigen which induces it inactivate the antigen and protect the body from disease

IgE provides

1.immunity against some parasites

2.complement killings of the cells and phagocytosis

3.secretions in the body

4. all of the above

β-Lymphocytes are often called simply

1.B cells

2.T cells

3.T Lymphocytes

4. none of these

Which of those immunoglobulin classes is mainly found in external secretions?

1.Ig A

2.Ig D

3.Ig M

4.Ig E

Monoclonal refers to

1.a single clone of antibody-producing cells

2.all the antibody molecules which are identical

3.the binding with same antigenic site with identical binding affinities

4. all of the above

Papain digest IgG into

1. two Fab fragments and one Fc fragment

2.three Fab fragments and two Fc fragments

3.two Fab fragments and two Fc fragments

4.three Fab fragments and three Fc fragments

Structures of anti-PCP antibody shows that the tight binding of PCP to the antibody is primarily due to

1. hydrophobic forces

2. electrostatic forces.

3.Van der Waals forces.

4.none of these

Type A blood

1.can be used to donate to type AB individuals

2.can be used to donate to type B individuals

3.contains type B antigens on the surface of red blood cells

4. can always be used to donate to an Rh+ individual

Which of the following are responsible for immune specificity?



3.T lymphocytes


Which species lack immunoglobulin light chains?






  1. Biochemistry -Water, pH and Macromolecules
  2. Biochemistry -Structure and Properties of Amino Acids
  3. Biochemistry -Thermodynamics and Free Energy
  4. Biochemistry -Protein Purification
  5. Biochemistry - Allosteric Effects
  6. Biochemistry -Immune System
  7. Biochemistry-Anti Bodies
  8. Biochemistry -Immunological Techniques
  9. Biochemistry MCQS PAPER SET 1
  10. Biochemistry MCQS PAPER SET 2
  11. Biochemistry MCQS PAPER SET 3
  12. Biochemistry MCQS PAPER SET 4
  13. Biochemistry MCQS PAPER SET 5
  14. Biochemistry MCQS PAPER SET 6
  15. Biochemistry MCQS PAPER SET 7
  16. Biochemistry MCQS PAPER SET 8
  17. Biochemistry MCQS PAPER SET 9
  18. Biochemistry MCQS PAPER SET 10
  19. Biochemistry MCQS PAPER SET 11
  20. Biochemistry MCQS PAPER SET 12
  21. Biochemistry MCQS PAPER SET 13
  22. Biochemistry MCQ Set 1
  23. Biochemistry MCQ Set 2
  24. Biochemistry MCQ Set 3
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